Liver cancer and diseases

hpbLiver cancer is 5th most common cancer in the United states and takes several lives every year. Dr. Singh Perform both open and laparoscopic liver surgery.

The liver is a maroon-brown organ in the human body. It is the second largest organ and the largest gland. The liver plays a major role in metabolism and has a number of functions in the body including glycogen storage, plasma protein synthesis, and drug detoxification.

The liver is among the few internal human organs capable of natural regeneration of lost tissue; as little as 25 percent of remaining liver can regenerate into a whole liver again.

liver cyt, hepatobiliary surgrey, Dr. Gajendra Singh Winston Salem, NC Liver cyst, Hepatobiliary surgery, Dr. Gajendra Singh Winston Salem, NC large liver cancer resected by right hepatectomy,Gajendra Singh MD, Forsyth Surgical Associates Winston Salem, NC

Diseases of the liver

Liver Cancer -

  • Primary hepatocellular carcinoma (HCC) or cholangiocarcinoma and metastatic cancers, usually from other parts of the gastrointestinal tract. They can be cured in early stages but the management can be difficult in the late stage in diseases. There are several option available including surgery, microwave or radiofrequency ablation, chemotherapy, radiation and finally palliative treatment
  • Hepatitis -
  • Inflammation of the liver, caused mainly by various viruses but also by some poisons, autoimmunity or hereditary conditions.
  • Cirrhosis - the formation of fibrous tissue in the liver, replacing dead liver cells. The death of the liver cells can for example be caused by viral hepatitis, alcoholism or contact with other liver-toxic chemicals.
  • Hemochromatosis - a hereditary disease causing the accumulation of iron in the body, eventually leading to liver damage.
  • Adenoma, cyst, Hemangioma - All these are benign lesions of the liver but often needs surgery to remove it. Sometime to avoid developing in caner or preventing complications like rupture or bleeding.
  • Wilson's disease - a hereditary disease which causes the body to retain copper.
  • Primary sclerosing cholangitis - an inflammatory disease of the bile duct, autoimmune in nature.
  • Primary biliary cirrhosis - autoimmune disease of small bile ducts.
  • Budd-Chiari syndrome - obstruction of the hepatic vein.
  • Gilbert's syndrome - a genetic disorder of bilirubin metabolism, found in about five percent of the population.
  • Glycogen storage disease type II - The build-up of glycogen causes progressive muscle weakness (myopathy) throughout the body and affects various body tissues, particularly in the heart, skeletal muscles, liver and nervous system.


Almost all the tumor, mass, cancer in the liver can be treated by surgery if they are in early stages. There are several other options if they are unresectable. Sometimes, when they are in advanced stage then Chemotherapy, radiation or palliative treatment in the only option. Several medical diseases like hepatitis can be managed medically. Usually these followed by medical liver specialist called as hepatologist and gastroenterologist.